I have read many an article making a reasoned case for why the U.S. should, as a last resort, take military action against Iran's nuclear facilities. In all those pieces I admit I have never encountered the argument that David Mamet makes here. To wit: that a failure to take military action against Iran is akin to practicing "human sacrifice" with the state of Israel (and, by the way, is anti-Semitic):
In abandonment of the state of Israel, the West reverts to pagan sacrifice, once again, making a burnt offering not of that which one possesses, but of that which is another's. As Realpolitik, the Liberal West's anti-Semitism can be understood as like Chamberlain's offering of Czechoslovakia to Hitler, a sop thrown to terrorism. On the level of conscience, it is a renewal of the debate on human sacrifice.
This is not the first time the idea has been raised that it is anti-Semitic to warn against the dangers of a war against Iran. Mitchell Bard asserted that there were "disturbing anti-Semitic undertones" in Defense Secretary Leon Panetta's observations that an attack on Iran would have negative consequences.